Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of amorolfine hydrochloride cas 78613-38-4 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk amorolfine hydrochloride cas 78613-38-4 made in China here and get pricelist from our factory. Good service and reasonable price are available.
Product Introduction:
1. Specification
|
Appearance |
White to off-white powder |
|
Assay |
99.0% Min |
|
Loss on Drying |
1.0% Max |
The latest specifications and COA will be sent upon request.
2. Packaging & shipping
|
Packaging |
R&D Sample Sizes: 1 g, 10 g, 100 g and 1kg bottle or aluminum bag for laboratory evaluation. |
|
Transport Classification |
Not regulated as a dangerous good |
|
Lead Time |
in stock |
|
Shipping Methods |
DHL, FedEx, air freight or sea freight |


3. Applications
Amorolfine hydrochloride is a antifungal reagent.Target: AntifungalAmorolfine is an antifungal showing activity against fungi pathogenic to plants, animals and humans. Amorolfine possesses a broad antifungal spectrum including dermatophytes, yeasts, dimorphic fungi and moulds and is not only fungistatic but fungicidal against most species . At 0.2, 2 and 5 micrograms/ml amorolfine did not have any significant inhibitory or enhancing effect on phagocytosis whether following simultaneous addition of blastospores and drug to the neutrophils, prior treatment of neutrophils for 2 h before addition of blastospores or prior treatment of blastospores for 2 h. Simultaneous addition of amorolfine resulted in a significant increase in killing at all concentrations. This increase was not significantly enhanced by either preincubation of neutrophils or blastospores for 2 h with the drug .
4. Spectrum

5. Related Articles
1. The low keratin affinity of efinaconazole contributes to its nail penetration and fungicidal activity in topical onychomycosis treatment.Antimicrob. Agents Chemother. 58(7) , 3837-42, (2014)
2. Characterization of Antifungal Activity and Nail Penetration of ME1111, a New Antifungal Agent for Topical Treatment of Onychomycosis.Antimicrob. Agents Chemother. 60 , 1035-9, (2016)
3. Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis.Antimicrob. Agents Chemother. 60 , 873-80, (2016)


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