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Amorolfine Hydrochloride CAS 78613-38-4

Amorolfine Hydrochloride CAS 78613-38-4

Amorolfine hydrochloride
CAS 78613-38-4
Purity: 99.0%Min | Appearance: White to off-white powder
Molecular Formula: C21H35NO·HCl | MW: 353.970
Einecs: 689-236-9
Synonyms: (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydron chloride

Product Introduction

Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of amorolfine hydrochloride cas 78613-38-4 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk amorolfine hydrochloride cas 78613-38-4 made in China here and get pricelist from our factory. Good service and reasonable price are available.

 

Product Introduction:

 

1.     Specification

Appearance

White to off-white powder

Assay

99.0% Min

Loss on Drying

1.0% Max

 

The latest specifications and COA will be sent upon request.

 

2.     Packaging & shipping

Packaging

R&D Sample Sizes: 1 g, 10 g, 100 g and 1kg bottle or aluminum bag for laboratory evaluation.

Transport Classification

Not regulated as a dangerous good

Lead Time

in stock

Shipping Methods

DHL, FedEx, air freight or sea freight

f-Amorolfine hydrochloride

s-Amorolfine hydrochloride

 

3.     Applications

Amorolfine hydrochloride is a antifungal reagent.Target: AntifungalAmorolfine is an antifungal showing activity against fungi pathogenic to plants, animals and humans. Amorolfine possesses a broad antifungal spectrum including dermatophytes, yeasts, dimorphic fungi and moulds and is not only fungistatic but fungicidal against most species . At 0.2, 2 and 5 micrograms/ml amorolfine did not have any significant inhibitory or enhancing effect on phagocytosis whether following simultaneous addition of blastospores and drug to the neutrophils, prior treatment of neutrophils for 2 h before addition of blastospores or prior treatment of blastospores for 2 h. Simultaneous addition of amorolfine resulted in a significant increase in killing at all concentrations. This increase was not significantly enhanced by either preincubation of neutrophils or blastospores for 2 h with the drug .

 

4.     Spectrum

t-78613-38-4-Amorolfine hydrochloride

 

5.     Related Articles

1. The low keratin affinity of efinaconazole contributes to its nail penetration and fungicidal activity in topical onychomycosis treatment.Antimicrob. Agents Chemother.   58(7) , 3837-42, (2014)
2. Characterization of Antifungal Activity and Nail Penetration of ME1111, a New Antifungal Agent for Topical Treatment of Onychomycosis.Antimicrob. Agents Chemother.   60 , 1035-9, (2016)
3. Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis.Antimicrob. Agents Chemother.   60 , 873-80, (2016)

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cerificate

 

 

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