Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of metronidazole cas 443-48-1 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk metronidazole cas 443-48-1 made in China here and get pricelist from our factory. Good service and reasonable price are available.
Product Introduction:
1. Specification
|
Appearance |
White to pale yellow crystals |
|
Assay |
99.0% Min |
|
Melting Range |
159~161 |
|
Loss on Drying |
1.0% Max |
The latest specifications and COA will be sent upon request.
2. Packaging & shipping
|
Packaging |
Bulk Packaging: 10kg ,25kg bag or drum or custom packaging upon request |
|
Transport Classification |
Not regulated as a dangerous good |
|
Lead Time |
in stock |
|
Shipping Methods |
DHL, FedEx, air freight or sea freight |
3. Applications
Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.Target: Antibacterial; AntiparasiticMetronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal. It is the drug of choice for first episodes of mild-to-moderate Clostridium difficile infection . Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria.
4. Spectrum
5. Related Articles
1. A trisubstituted benzimidazole cell division inhibitor with efficacy against Mycobacterium tuberculosis.PLoS ONE 9(4) , e93953, (2014)
2. Indirect electroreduction as pretreatment to enhance biodegradability of metronidazole.J. Hazard. Mater. 278 , 172-9, (2014)
3. Carrier Mediated Distribution System (CAMDIS): a new approach for the measurement of octanol/water distribution coefficients.Eur. J. Pharm. Sci. 68 , 68-77, (2015)
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