Bivalirudin CAS 128270-60-0

Name: China Customized Bivalirudin CAS 128270-60-0 Manufacturers Suppliers Factory - Dayang Chem
Brand: Dayang Chem
SKU: 297218458

Bivalirudin
CAS 128270-60-0
Purity: 98.0%Min | Appearance: White to off-white powder
Molecular Formula: C98H138N24O33 | MW: 2295.31
Einecs: 811-536-7
Synonyms: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[2-[[2-[[2-[[[(2S)-1-[(2S)-2-[[[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxyethylidene]amino]-1,4-dihydroxy-4-iminobutylidene]amino]-1-hydroxyethylidene]amino]-3-carboxy-1-hydroxypropylidene]amino]-1-hydroxy-3-phenylpropylidene]amino]-4-carboxy-1-hydroxybutylidene]amino]-4-carboxy-1-hydroxybutylidene]amino]-3-methylpentanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-4-carboxy-1-hydroxybutylidene]amino]-4-carboxy-1-hydroxybutylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-4-methylpentanoic acid;hirulog-1;H-fPRPGGGGNGDFEEIPEEYL-OH

Product Introduction

Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of bivalirudin cas 128270-60-0 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk bivalirudin cas 128270-60-0 made in China here and get pricelist from our factory. Good service and reasonable price are available.

Product Introduction:

1. Specification

Appearance	White to off-white powder
Assay	98.0% Min
Loss on Drying	1.0% Max

The latest specifications and COA will be sent upon request.

2. Packaging & shipping

Packaging	R&D Sample Sizes: 1 g, 10 g, 100 g and 1kg bottle or aluminum bag for laboratory evaluation.
Transport Classification	Not regulated as a dangerous good
Lead Time	in stock
Shipping Methods	DHL, FedEx, air freight or sea freight

f-Bivalirudin

s-Bivalirudin

3. Applications

Bivalirudin Trifluoroacetate is a synthetic 20 residue peptide which reversibly inhibits thrombin.IC50 Value:Target: thrombinin vitro: Eptifibatide (8 mg/mL) added together with a low (70 ng/mL) concentration of bivalirudin (a direct thrombin inhibitor) effectively (approximately 90%) reduced platelet aggregation induced by thrombin (0.2 U/mL) . In thrombin generation assay (TGA), bivalirudin had no effect on these parameters up to 10 mol/l . Bivalirudin-facilitated binding of MPO to BAEC resulted also in functional changes in terms of increased NO consumption as well as enhanced MPO-mediated redox modifications .in vivo: The use of bivalirudinprevented further increase in antiheparin/PF4 antibody IgG levels in rats . Three animals in the 500-mg/kg/24 h group, and 7 animals in the 2000-mg/kg/24 h group in the toxicokinetic assessment phase of the study were found dead or euthanized in extremis (following blood sampling). Plasma concentrations of bivalirudin appeared to be linear and dose independent .Clinical trial: Antithrombotic Effects of Ticagrelor Versus Clopidogrel . Phase 4

4. Spectrum

t-128270-60-0-Bivalirudin

5. Related Articles

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