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Andrographolide CAS 5508-58-7

Andrographolide CAS 5508-58-7

Andrographolide
CAS 5508-58-7
Purity: 98.0%Min | Appearance: White to off-white powder
Molecular Formula: C20H30O5 | MW: 350.449
Einecs: 226-852-5
Synonyms: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one;14α-andrographolide;AND

Product Introduction

Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of andrographolide cas 5508-58-7 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk andrographolide cas 5508-58-7 made in China here and get pricelist from our factory. Good service and reasonable price are available.

 

Product Introduction:

 

1.     Specification

Appearance

White to off-white powder

Assay

98.0% Min

Loss on Drying

1.0% Max

 

The latest specifications and COA will be sent upon request.

 

2.     Packaging & shipping

Packaging

R&D Sample Sizes: 1 g, 10 g, 100 g and 1kg bottle or aluminum bag for laboratory evaluation.

Transport Classification

Not regulated as a dangerous good

Lead Time

in stock

Shipping Methods

DHL, FedEx, air freight or sea freight

f-Andrographolide

s-Andrographolide

 

3.     Applications

Andrographolide is a NF-B inhibitor, which inhibits NF-B activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IB degradation or p50/p65 nuclear translocation.

 

4.     Spectrum

t-5508-58-7-Andrographolide

 

5.     Related Articles

1. Andrographolide prevents high-fat diet-induced obesity in C57BL/6 mice by suppressing the sterol regulatory element-binding protein pathway.J. Pharmacol. Exp. Ther.   351(2) , 474-83, (2014)
2. Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats.Toxicol. Appl. Pharmacol.   280(1) , 1-9, (2014)
3. Andrographolide inhibits TNF-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells.Biochem. Pharmacol.   91(1) , 40-50, (2014)

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