Lanatoside C CAS 17575-22-3

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Product Introduction:

1.     Specification

The latest specifications and COA will be sent upon request.

2.     Packaging & shipping

3.     Applications

Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 M for dengue virus infection in HuH-7 cells. Target:in vitro: Dose-dependent reduction in dengue viral RNA and viral proteins synthesis were also observed upon treatment with increasing concentrations of Lanatoside C. Time of addition study indicated that Lanatoside C inhibits the early processes of the dengue virus replication cycle. Furthermore, Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya and Sindbis virus as well as the human enterovirus 71. Lanatoside C possesses broad spectrum antiviral activity against several groups of positive-sense RNA viruses.

4.     Spectrum

5.     Related Articles

1. Identification of natural compound inhibitors for multidrug efflux pumps of Escherichia coli and Pseudomonas aeruginosa using in silico high-throughput virtual screening and in vitro validation.PLoS ONE   9(7) , e101840, (2014)
2. Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old.Chin. Med. Sci. J.   21(1) , 16-9, (2006)
3. [Cardiac glycosides in complex treatment of patients with heart failure and supraventricular arrhythmias].Klin. Med. (Mosk.)   83(7) , 59-63, (2005)

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