Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of isatin cas 91-56-5 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk isatin cas 91-56-5 made in China here and get pricelist from our factory. Good service and reasonable price are available.
Product Introduction:
1. Specification
|
Appearance |
Red powder |
|
Assay |
98.0% Min |
|
Melting Range |
193~195 |
|
Loss on Drying |
1.0% Max |
The latest specifications and COA will be sent upon request.
2. Packaging & shipping
|
Packaging |
Bulk Packaging: 10kg ,25kg bag or drum or custom packaging upon request |
|
Transport Classification |
Not regulated as a dangerous good |
|
Lead Time |
in stock |
|
Shipping Methods |
DHL, FedEx, air freight or sea freight |
3. Applications
Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 of 3 M. Also binds to central benzodiazepine receptors (IC50 against clonazepam, 123 M). Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity. Shows effect on the serotonergic system.
4. Spectrum
5. Related Articles
1. Unprecedented one-pot, domino tertiary alcohol protection-Michael type addition of halides to Morita-Baylis-Hillman adduct of isatin with RCOX/K2CO3: diastereoselective synthesis of oxindole appended -halo esters.Org. Lett. 15(6) , 1186-9, (2013)
2. Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.J. Med. Chem. 54 , 5320, (2011)
3. Reactivity of dinuclear copper(II) complexes towards melanoma cells: Correlation with its stability, tyrosinase mimicking and nuclease activity.J. Inorg. Biochem. 149 , 49-58, (2015)
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