DL-Mevalonic Acid Delta-lactone CAS 674-26-0

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Product Introduction:

1.     Specification

The latest specifications and COA will be sent upon request.

2.     Packaging & shipping

3.     Applications

DL-Mevalonolactone (()-Mevalonolactone;Mevalolactone) is the -lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (?m), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling.

4.     Spectrum

5.     Related Articles

1. In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.Br. J. Cancer   111(8) , 1562-71, (2014)
2. Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.Bioorg. Med. Chem.   17(23) , 7915-23, (2009)
3. Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS.J. Lipid Res.   48(5) , 1212-20, (2007)

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