Dayang Chem (Hangzhou) Co., Ltd. is one of the leading manufacturers and suppliers of benfotiamine cas 22457-89-2 in China, specialized in providing high quality customized chemicals. Welcome to wholesale bulk benfotiamine cas 22457-89-2 made in China here and get pricelist from our factory. Good service and reasonable price are available.
Product Introduction:
1. Specification
|
Appearance |
White to off-white powder |
|
Assay |
99.9% Min |
|
Melting Range |
164~165 |
|
Loss on Drying |
1.0% Max |
The latest specifications and COA will be sent upon request.
2. Packaging & shipping
|
Packaging |
Bulk Packaging: 10kg ,25kg bag or drum or custom packaging upon request |
|
Transport Classification |
Not regulated as a dangerous good |
|
Lead Time |
in stock |
|
Shipping Methods |
DHL, FedEx, air freight or sea freight |
3. Applications
Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1); an antioxidant dietary supplement.IC50 value:Target: Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)?protein kinase C (PKC) pathwayof hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
4. Spectrum
5. Related Articles
1. Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.BMC Pharmacol. 8 , 10, (2008)
2. The detrimental effects of acute hyperglycemia on myocardial glucose uptake.Life Sci. 105(1-2) , 31-42, (2014)
3. The effect of benfotiamine on mu-opioid receptor mediated antinociception in experimental diabetes.Exp. Clin. Endocrinol. Diabetes 122(3) , 173-8, (2014)
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