Doxepin Hydrochloride CAS 1229-29-4

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Product Introduction:

1.     Specification

The latest specifications and COA will be sent upon request.

2.     Packaging & shipping

3.     Applications

Doxepin HCl is a tricyclic antidepressant that is marketed worldwide.Target: SSRIsDoxepin inhibits the reuptake of serotonin and norepinephrine and acts as a antagonist at various serotonergic, adrenergic, musacrinic, dopaminergic and histaminergic receptors . In the doxepin-treated patients who completed the study (N = 20, 47.6+/-11.3), medication significantly increased sleep efficiency after acute (night 1, p < or = .001) and subchronic (night 28, p < or = .05) intake compared with the patients who received placebo (N = 20, 47.4+/-16.8 years of age). Doxepin to cause significantly (p < or = .05) better global improvement at the first day of treatment .

4.     Spectrum

5.     Related Articles

1. Differential thermodynamic driving force of first- and second-generation antihistamines to determine their binding affinity for human H1 receptors.Biochem. Pharmacol.   91(2) , 231-41, (2014)
2. Transbuccal delivery of doxepin: studies on permeation and histological investigation.Int. J. Pharm.   477(1-2) , 650-4, (2014)
3. [Prolonged toxic coma and anisocoria secondary to doxepin, lorazepam and phenobarbital poisoning--case study].Prz. Lek.   69(8) , 624-6, (2012)

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